Sulfasalazine is an anti-bacterial and anti-inflammatory drug which is used primarily to treat IBD (inflammatory bowel disease) and colitis in cats and dogs. It is also used to reduce the actions of substances in the body which can cause inflammation

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Using Sulfasalazine for Your Pet. Because sulfasalazine is a drug designed for human use, it comes in tablets that are sized much too large for many dogs. The tablets are generally given at 500 milligrams and 1000 milligrams. Most dogs will require a dosage of between 15 and 25 milligrams per pound, provided every 8 hours or so.

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Sulfasalazine and related drugs are often used in dogs when IBD is limited to the large intestine. However, because side effects include keratoconjunctivitis sicca, tear production should be monitored regularly. Treatment of Patients With Severe PLE

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